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Clinical studies have shown Tesofensine can result in up to 10% body weight reduction, which is greater than many traditional weight loss medications

Additionally, conditions such as severe cardiac or pulmonary insufficiency that lead to reduced peripheral perfusion, lactic acidosis, liver disease, alcohol dependence, or the use of intramuscular contrast agents for radiographic imaging also represent exclusion criteria due to the increased risk of adverse effects, particularly lactic acidosis (80, 121)

For someone with diverticulosis, maintaining a strong gut barrier could be a key factor in preventing bacteria from getting trapped and causing an infection